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However, many of the studies that showed increased
tumor development used animals that had been
genetically engineered or treated with cancer-causing
chemicals so as to be pre-disposed to develop cancer
in the absence of RF exposure. Other studies exposed
the animals to RF for up to 22 hours per day. These
conditions are not similar to the conditions under which
people use wireless phones, so we don't know with
certainty what the results of such studies mean for
human health.
Three large epidemiology studies have been published
since December 2000. Between them, the studies
investigated any possible association between the use
of wireless phones and primary brain cancer, glioma,
meningioma, or acoustic neuroma, tumors of the brain
or salivary gland, leukemia, or other cancers. None of
the studies demonstrated the existence of any harmful
health effects from wireless phone RF exposures.
However, none of the studies can answer questions
about long-term exposures, since the average period of
phone use in these studies was around three years.
5. What research is needed to decide whether RF
exposure from wireless phones poses a health risk?
A combination of laboratory studies and epidemiological
studies of people actually using wireless phones would
provide some of the data that are needed. Lifetime
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Safety
animal exposure studies could be completed in a few
years. However, very large numbers of animals would be
needed to provide reliable proof of a cancer promoting
effect if one exists. Epidemiological studies can provide
data that is directly applicable to human populations, but
10 or more years follow-up may be needed to provide
answers about some health effects, such as cancer.
This is because the interval between the time of
exposure to a cancer-causing agent and the time tumors
develop — if they do — may be many, many years. The
interpretation of epidemiological studies is hampered by
difficulties in measuring actual RF exposure during day-
to-day use of wireless phones. Many factors affect this
measurement, such as the angle at which the phone is
held, or which model of phone is used.
6. What is the FDA doing to find out more about the
possible health effects of wireless phone RF?
The FDA is working with the U.S. National Toxicology
Program and with groups of investigators around the
world to ensure that high priority animal studies are
conducted to address important questions about the
effects of exposure to radio frequency energy (RF). The
FDA has been a leading participant in the World Health
Organization International Electromagnetic Fields (EMF)
Project since its inception in 1996. An influential result of
this work has been the development of a detailed

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