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Safety Data Sheet
™ ®
DuPont Suva 410A Refrigerant
Version 2.0
Revision Date 03/23/2015
Carcinogenicity
Mutagenicity
Reproductive toxicity
Teratogenicity
Further information
Difluoromethane (HFC-32)
Inhalation 4 h LC50
Inhalation Low Observed
Adverse Effect
Concentration (LOAEC)
Inhalation No Observed
Adverse Effect
Concentration
Skin irritation
Eye irritation
Skin sensitization
Repeated dose toxicity
Ref. 130000050990
: Not classifiable as a human carcinogen.
Overall weight of evidence indicates that the substance is not
carcinogenic.
: Animal testing did not show any mutagenic effects.
Evidence suggests this substance does not cause genetic damage in
cultured mammalian cells.
Did not cause genetic damage in cultured bacterial cells.
: No toxicity to reproduction
Animal testing showed no reproductive toxicity.
: Animal testing showed no developmental toxicity.
: Cardiac sensitisation threshold limit : 490000 mg/m3
: > 520000 ppm , Rat
: > 350000 ppm , Dog
Cardiac sensitization
: 350000 ppm , Dog
Cardiac sensitization
: No skin irritation, Not tested on animals
Not expected to cause skin irritation based on expert review of the
properties of the substance.
: No eye irritation, Not tested on animals
Not expected to cause eye irritation based on expert review of the
properties of the substance.
: Does not cause skin sensitisation., Not tested on animals
Not expected to cause sensitization based on expert review of the
properties of the substance.
There are no reports of human respiratory sensitization.
: Inhalation
Rat
-
No toxicologically significant effects were found.
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