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Se han analizado los valores de acetaldehído hasta 0,6 mg/dL (0,14 mM), acetominofen hasta 20 mg/dL
(1,3 mM), ácido acetilsalicílico hasta 50 mg/dL (2,8 mM), ácido ascórbico hasta 3 mg/dL (0,17 mM), ácido
ß-hidroxibutírico hasta 202 mg/dL (16 mM), dopamina hasta 13 mg/dL (0,85 mM), formaldehído hasta
1,2 mg/dL (0,40 mM), glicina hasta 98 mg/dL (13 mM), ácido pirúvico hasta 2,6 mg/dL (0,24 mM) y ácido
úrico hasta 25 mg/dL (1,5 mM) y se ha descubierto que no interfieren con los resultados del lactato (Lac). Se
analizaron los niveles de hematocrito entre 25 y 67% y se ha descubierto que no interfieren en los resultados
del lactato (Lac).
Referencias
1. D.S. Young, Effects of Drugs on Clinical Laboratory Tests, 3rd ed. (Washington, DC: American Association
of Clinical Chemistry, 1990).
2. D.B. Sacks, Carbohydrates, in Tietz Textbook of Clinical Chemistry, Second Edition, ed. C.A. Burtis and E.R.
Ashwood, (Philadelphia: W.B. Saunders Company, 1994).
3. NCCLS. Evaluation of Precision Performance of Clinical Chemistry Devices; Approved Guideline. NCCLS
document EP5-A [ISBN 1-56238-368-X]. NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania
19087-1898, USA 1999.
4. NCCLS. Method Comparison and Bias Estimation Using Patient Samples; Approved Guideline. NCCLS document
EP9-A [ISBN 1-56238-283-7]. NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898,
USA 1995.
5. P.J. Cornbleet and N. Gochman, "Incorrect Least-Squares Regression Coefficients in Method Comparison
Analysis," Clinical Chemistry 25:3, 432 (1979).
6. NCCLS. Interference Testing in Clinical Chemistry; Proposed Guideline. NCCLS document EP7-P [ISBN 1-56238-
020-6]. NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898, USA 1986.
7. Porter WH, Crellin M, Rutter PW, Oeltgen P. Interference by Glycolic Acid in the Beckman Synchron Method
for Lactate: A Useful Clue for Unsuspected Ethylene Glycol Intoxication. Clin Chem 2000; 46:874-875.
8. Morgan, TJ, Clark C, Clague A. Artifactual elevation of measured plasma L-lactate concentration in the
presence of glycolate. Crit Care Med 1999; 27:2177-2179.
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Art: 714184-04D
Rev. Date: 04/16/04
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